2026 Mercedes-Benz E-Class Sedan Drivetrain Comparison
The E 350 4MATIC® Sedan utilizes an all-wheel drive system, while the standard E 350 is rear-wheel drive.Drivers in Glendale must choose between maximum fuel efficiency or enhanced winter weather traction.Review the objective engine and drivetrain differences below before exploring our available luxury sedan inventory.The powertrain configuration determines how your luxury vehicle handles diverse Wisconsin driving conditions.To understand how these models compare in terms of cabin amenities and technology, read our complete 2026 Mercedes-Benz E-Class Sedan overview.If you are comparing the entry-level models, the distinction lies entirely in the drivetrain.Both the E 350 Sedan and the E 350 4MATIC® Sedan share the same 2.0L inline-4 turbo engine with mild hybrid drive.You can browse our current Glendale Mercedes-Benz E-Class availability to find either configuration.
Performance and Traction Metrics
| Specification |
E 350 Sedan |
E 350 4MATIC® Sedan |
E 450 4MATIC® Sedan |
| Engine Type |
2.0L Inline-4 Turbo |
2.0L Inline-4 Turbo |
3.0L Inline-6 Turbo |
| Drivetrain |
Rear-Wheel Drive |
4MATIC® All-Wheel Drive |
4MATIC® All-Wheel Drive |
| Horsepower |
255 HP |
255 HP |
375 HP |
| Torque |
295 lb-ft |
295 lb-ft |
369 lb-ft |
Choosing the Right Configuration
The standard E 350 Sedan utilizes rear-wheel drive. This setup maximizes the EPA-estimated 33 MPG highway rating, when properly equipped, making it an excellent choice for drivers prioritizing fuel economy on clear roads.Upgrading to the E 350 4MATIC® Sedan adds intelligent all-wheel drive.This system continuously monitors wheel slip and sends power to the tires with the most grip.For daily commuters in Milwaukee, this translates to confident handling and improved stability when navigating through heavy snow or sudden rain showers.
The E 450 4MATIC® Sedan represents a significant step up in raw performance.It replaces the 4-cylinder engine with a robust 3.0L inline-6 turbo, generating 375 horsepower.This massive increase in output ensures you have effortless acceleration for safe passing maneuvers on Interstate 43. You can review the exact specifications of this inline-6 architecture on the official Mercedes-Benz engineering page.
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